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Enzyme Kinetics and Mechanis is a comprehensive textbook on steady-state enzyme kinetics. Organized according to the experimental process, the text covers kinetic mechanism, relative rates of steps along the reaction pathway, and chemical mechanism—including acid-base chemistry and transition state structure. Practical examples taken from the literature demonstrate theory throughout. The book also features numerous general experimental protocols and how-to explanations for interpreting kinetic data. Written in clear, accessible language, the book will enable graduate students well-versed in biochemistry to understand and describe data at the fundamental level. Enzymologists and molecular biologists will find the text a useful reference.

• Sales Rank: #1482561 in eBooks
• Published on: 2012-08-20
• Released on: 2012-08-20
• Format: Kindle eBook

Review

"Enzyme Kinetics and Mechanism is an advanced text with meticulous details...[that] gives 'hands on' explanations to the target readership..."

Journal of the Higher Education Academy Physical Sciences Centre, June 2008

About the Author

Paul F. Cook is the Grace B. Kerr Centennial Professor of Chemistry and Biochemistry at the University of Oklahoma. His awards and achievements twice included the Alexander von Humboldt Research Fellowship and he was the recipient of the National Institutes of Health Research Career Development Award from 1983 to 1988. Professor Cook is Associate Editor of Protein and Peptide Letters and Executive Editor of Proteins and Proteomics.

W.W. Cleland is the M.J. Johnson Professor and Steenbock Professor of Chemical Science at the Enzyme Institute at University of Wisconsin-Madison. In the early 1960s, Cleland's landmark papers created a theoretical framework for the study of steady-state kinetics of multisubstrate enzymes and laid the foundation for all subsequent steady-state studies. He serves on the editorial boards of Journal of Biological Chemistry and of Biochemistry. Recognized by many as the "father of modern enzyme kinetics," Professor Cleland was elected to the National Academy of Sciences in 1985.

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From the Back Cover

“[This] is a book about design in the .NET world, driven in an agile manner and infused with the products of the enterprise patterns community. [It] shows you how to begin applying such things as TDD, object relational mapping, and DDD to .NET projects...techniques that many developers think are the key to future software development.... As the technology gets more capable and sophisticated, it becomes more important to understand how to use it well. This book is a valuable step toward advancing that understanding.” –Martin Fowler, author of Refactoring and Patterns of Enterprise Application Architecture   Patterns, Domain-Driven Design (DDD), and Test-Driven Development (TDD) enable architects and developers to create systems that are powerful, robust, and maintainable. Now, there’s a comprehensive, practical guide to leveraging all these techniques primarily in Microsoft .NET environments, but the discussions are just as useful for Java developers.   Drawing on seminal work by Martin Fowler (Patterns of Enterprise Application Architecture) and Eric Evans (Domain-Driven Design), Jimmy Nilsson shows how to create real-world architectures for any .NET application. Nilsson illuminates each principle with clear, well-annotated code examples based on C# 1.1 and 2.0. His examples and discussions will be valuable both to C# developers and those working with other .NET languages and any databases–even with other platforms, such as J2EE. Coverage includes   ·        Quick primers on patterns, TDD, and refactoring ·        Using architectural techniques to improve software quality ·        Using domain models to support business rules and validation ·        Applying enterprise patterns to provide persistence support via NHibernate ·        Planning effectively for the presentation layer and UI testing ·        Designing for Dependency Injection, Aspect Orientation, and other new paradigms  

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About the Author

Jimmy Nilsson owns and runs the Swedish consulting company JNSK AB. He has written numerous technical articles and two books. He has also been training and speaking at conferences, but above everything else, he is a developer with almost 20 years of experience (www.jnsk.se/weblog/).

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Product details

Hardcover: 576 pages

Publisher: Addison-Wesley Professional; 1 edition (May 18, 2006)

Language: English

ISBN-10: 0321268202

ISBN-13: 978-0321268204

Product Dimensions:

7.3 x 1.4 x 9.5 inches

Shipping Weight: 2.1 pounds (View shipping rates and policies)

Average Customer Review:

3.8 out of 5 stars

26 customer reviews

Amazon Best Sellers Rank:

#1,123,415 in Books (See Top 100 in Books)

I have come back to this book after first digging into it when it first came out. At that time, I got bogged down and never really made it very far into the book. Here's why: A reader needs a basic conceptual familiarity with DDD before tackling this book. I'd suggest Domain-Driven Design: Tackling Complexity in the Heart of Software and Patterns of Enterprise Application Architecture (Addison-Wesley Signature Series). You might be able to get a running start by reading the free e-book "Domain Driven Design Quickly" ([...] but the Fowler book is particularly helpful, since it catalogs and explains a number of the patterns used in Nilsson's book.Don't assume this book is outdated because it uses NHibernate instead of LINQ or the ADO Entity Framework. If you are a true DDD developer, neither product is quite 'there' yet, and NHibernate remains the best ORM framework available. And if the Entity Framework does become a viable ORM product in Version 2, the skills taught in this book should transfer easily.In short, this book presents a really good nuts-and-bolts approach to explaining how to do DDD, but it assumes you already have a pretty good understanding of what DDD is all about.

I really enjoyed reading this book. Jimmy has a very conversational writing style. He will show some code, talk about the pros and cons, make a change, talk about that change and repeat until he has something he is satisfied with. This was very helpful to me as it demonstrated that he has gone through the same growing process that we all need to take as software developers. He is not lecturing from a tower; he is a common programmer who has be able to develop some excellent techniques through research and experience working with others who also seek to be the best they can. His examples are clear and meaningful. He shows how you can actually use TDD to grow a domain model, which is something that has certainly been lacking from other resources I have used in the past. I read the book because I feel like my dev team needs a better focus and I am now more convinced that DDD and TDD will help us focus on creating maintainable code for our enterprise.

Great read for those conversant in C# and perhaps object-oriented language. Take time to read in-depth to capture this material.

The book provides a massive detailed walk through the construction of the domain-driven framework creation. It is in Jimmy Nilsson's conversational tone and that makes the book very interesting.I do wish there were a few diagrams to tie each chapter together, but that is for the reader to do.

This is really an exellent book on DDD, I read soon after the Evans book and I must admit that is really worth money I spent on it. Sure the book is not for beginners, and it is not an introduction to DDD, I think that a background on the subject is needed to fully appreciate this book.Alk.

Good

Read fowler's and Evan's, the book is very good but it is an extension of books of the two authors. So, to understand it completely it is better to read those before.I have not read the books that this is based but I have enjoyed it a lot.

So far I have just passed half way and I loved every page.I wish I had more time to go through it faster.It is very well explained and the author has a good sense of humor.

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Hoping to settle down after an adventurous military career, Sam Vetch learns that his wife was once the mate of a notorious Apache who has come to claim her in a duel to the death with Sam. Original.

• Sales Rank: #1727792 in Books
• Brand: Brand: Leisure Books
• Published on: 2010-05-01
• Original language: English
• Number of items: 1
• Dimensions: .71" h x 4.15" w x 6.70" l, .26 pounds
• Binding: Mass Market Paperback
• 247 pages

• Used Book in Good Condition

About the Author

Theodore Victor Olsen (April 25, 1932 in Rhinelander, Wisconsin – July 13, 1993 in Rhinelander) was an American western fiction author.

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This scarce antiquarian book is a facsimile reprint of the original. Due to its age, it may contain imperfections such as marks, notations, marginalia and flawed pages. Because we believe this work is culturally important, we have made it available as part of our commitment for protecting, preserving, and promoting the world's literature in affordable, high quality, modern editions that are true t

• Published on: 2007
• Binding: Paperback
• 576 pages

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